The role of TP53INP1 in suppressing cell migration is also of particular interest for cancer therapy, since the expression of genes involved in cell to cell and cell to extracellular matrix adhesion is significantly altered in some highly aggressive carcinomas (Hanahan and Weinberg, 2011), and TP53INP1 can potentially be an important player in invasion-metastasis cascade by targeting the genes. This evidence concerns the gene TP53INP1 and cancer.