Among these, we can highlight the use of antioxidant therapy, such as ROS scavengers and vitamins, SOD mimetics or NAD(P)H oxidase inhibitors that has experimentally shown to attenuate or prevent the development of hypertension (Chen et al., 2001; Landmesser et al., 2003; Costa et al., 2009; Queiroz et al., 2012). This evidence concerns the gene SOD1 and hypertensive disorder.