SMO and Parkinson disease: Exceptional PD-related examples of seemingly active miRNA-spliced transcripts predicted interactions include USP13, which promotes smooth (SMO) signaling by preventing its ubiquitination (Xia et al., 2012), RGS3 which contributes to neural progenitor/stem cell regulation (Qiu et al., 2010) and MGAT1, involved in multiple sclerosis (Grigorian et al., 2012).