The ED of ICAM-2 contains six N-glycosylation sites (asparagines [Asn] residues; amino acids # 47, 82, 105, 153, 178 and 187) [17], a frequent post translational modification of CAM proteins and a modification known, in general, to influence CAM structure and function and to impact the phenotype of tumor cells [18-20]. This evidence concerns the gene ICAM2 and neoplasm.