CST4 and neoplasm: This stratification based on the Cystatin SN expression level was also observed for pN0 patients (P < 0.001 and P < 0.001, respectively), stage II patients (P < 0.001 and P < 0.001, respectively), tumor grade 1 patients (P = 0.003 and P = 0.001, respectively) and tumor grade 2 patients (P = 0.001 and P = 0.002, respectively) (Table 3).