It should be mentioned that a chronic study observing the impact of myocardial overexpression of Sema3a on long-term survival, left ventricular remodelling and telemetry monitored ‘natural’ arrhythmias in this model is essential to conclude the ‘general’ effect of myocardial overexpression of Sema3a in this model. This evidence concerns the gene SEMA3A and Arrhythmia.