Semiquantitative analysis of NF-κB expression in the liver by image analysis techniques showed that there was a 26.3% increase in obese rats compared to controls (0.385 ± 0.031 versus 0.306 ± 0.028, P = 0.001) and an 18.9% decrease in the fenofibrate group compared to the obesity group (0.313 ± 0.045 versus 0.385 ± 0.031, P < 0.05). This evidence concerns the gene NFKB1 and Obesity.