EGFR and hepatocellular carcinoma: After demonstrating the specific binding of Alexa680-ZEGFR:1907 toward EGFR in both in vitro cell culture and in vivo xenografts of human HCC cell lines, this fluorescent affibody probe was used for optical imaging of nude mice bearing subcutaneous Hep3B, PLC/PRF/5, or HepG2 xenografts.