Linear regression analysis showed that TIMP-1 levels were associated with the 372 T/C genetic polymorphism of TIMP-1 (regression coefficient = 114.4; 95% CI = 31.71 to 197.14; P = 0.007), but not with site of infection (regression coefficient = 105.7; 95% CI = -45.12 to 256.48; P = 0.17). This evidence concerns the gene TIMP1 and infection.