Recently, a serology study on females diagnosed with tubal factor infertility (TFI) was performed, and it was shown by ELISA that IgG antibodies to C. trachomatis HSP60 were of the IgG1 and IgG3 subclass and that no antibodies against human HSP60 could be detected [25]. Here, HSPD1 is linked to tubal factor infertility.