TARDBP and sarcoma: These include mutations in genes encoding Cu/Zn superoxide dismutase 1 SOD1; [1]; angiogenin [2,3]; TARDBP encoding TAR DNA binding protein 43 kDa or TDP-43; [4-6] , FUS/TLS encoding a RNA processing protein fused in sarcoma/translocated in liposarcoma; [7,8] and an expanded hexanucleotide repeat in the non-coding region of C9ORF72[9,10].