BRCA1 and breast carcinoma: In addition, the longitudinal cumulative incidence over time predicted by the DEABM was comparable to previously assessed risk in populations with germline BRCA1 mutation [46]–[50] (Figure 7B), demonstrating the ability of the DEABM to plausibly reproduce the incidences of invasive breast cancer in both wild-type/sporadic and BRCA1 mutant populations.