XRCC1 and urinary bladder carcinoma: XRCC1 Arg194Trp In pooled analysis, a significantly increased risk of bladder cancer was observed in dominant model (OR = 1.199, 95% CI: 1.021,1.408, Pheterogeneity = 0.372 Figure 2A) and allele comparison (OR = 1.200, 95% CI: 1.057,1.362, Pheterogeneity = 0.107 Figure 2B).