The network analysis indicated alterations in a number of cancer related pathways, including p38 MAPK, PI3K/AKT, ERK/MAPK and NF-κB signaling pathways, and a potential role of TGFA, ErbB2, and IL-1/IL-1R in young women with breast cancer (Figure 2B). This evidence concerns the gene NFKB1 and breast cancer.