Furthermore, the 16p13.11 deletion serves as the second paradigm for microdeletions uncovering mutations of genes on the non-deleted homolog—the other being Bernard-Soulier syndrome due to deletion 22q11.2 and mutation of GP1BB on the non-deleted homolog Budarf et al., 1995; Ludlow et al., 1996. Here, GP1BB is linked to Bernard-Soulier syndrome.