Increased expression of pro-inflammatory cytokines (IL1, IL6, IL18), genes involved in cytokine-cytokine signaling cascades (IL1R, IL6R, TNFAIP3, TNFAIP6, TNFSF13B, PTX3), cell-cell adhesion (CDH1, ICAM1, FN1, ITGA2), tissue remodeling (VEGF), extracellular matrix (ECM), and proteolysis (SERPINE1) characterized the inflammatory response induced by CDV in immortalized keratinocytes and HPV+ tumor cells. The gene discussed is PTX3; the disease is neoplasm.