Activation of LXR/RXR pathways following CDV treatment was exclusively observed in the immortalized keratinocytes and HPV+ tumor cells (Additional file 3: Table S1) and was associated with increased mRNA levels of the toll-like receptor TLR4, ABC transporters (ABCG1, ABCA1), inflammatory cytokines (IL1A, IL6, IL18), cytokine receptors (IL1R1, IL1RN, IL1R2, IL36RN), matrix metallopeptidase (MMP9), and/or cyclooxygenase (PTGS2). This evidence concerns the gene TLR4 and neoplasm.