VDR and osteoporosis: To understand the exactrole of the polymorphism, it is necessarynot only to compare the entire genome of thepeople of the same genotype either healthyor patient, but also toanalyze the genomic organizationof the VDR locus and to identifythe relationship between the genes presentin the same chromosomal area and to identifyother possible gene-gene interactionsthroughout the whole genome to be able toanalyze the association mechanism of thepolymorphism with a phenotype like osteoporosis.