Considering the results above, the PPARalpha/SREBP-1c ratio was lower in the HF group compared to the SC group (P = 0.0176), higher in the SC/BZ group compared to the SC group (P<0.0001) and higher in the HF/BZ group compared to the untreated HF group (P = 0.008) (Figure 5A). This evidence concerns the gene SREBF1 and hydrops fetalis.