Bull A was not a carrier of any known genetic diseases in Japanese Black cattle (e.g., BAND3 deficiency, factor XIII deficiency, claudin-16 deficiency, molybdopterin cofactor sulfurase deficiency, Chediak-Higashi syndrome, factor XI deficiency, and Marfan syndrome-like disease) [3]–[9]. The gene discussed is CLDN16; the disease is hyperinsulinemic hypoglycemia, familial, 4.