RBPJ and infection: These studies show that in kidneys of infected mice, binding of repressors, including HDACs, YY1, Rbpj/CBF-1, CIR, and Daxx, to viral genomes has three phases: binding is initially detected at the earliest phase of infection, prior to activation of viral gene expression and DNA replication, and then falls as RNA polymerase II is recruited to viral promoters and viral gene expression is activated.