These novel target genes are A2BP1 (RBFOX1), HSD17B10, NLGN1, and NTRK2. Furthermore, our pilot study examining the expression of these six transcriptional targets of RORA in postmortem brain tissues from individuals with ASD and that of age-matched controls shows an average reduction of all targets in the autism samples, although the differences between combined cases and combined controls were not statistically significant, all exhibiting P >0.05. The gene discussed is NLGN1; the disease is autism.