Another caveat is that the list of RORA targets does not replicate all of the several targets identified in the mouse cerebellum by ChIP-quantitative PCR analyses[29] other than ITPR1. We do not know the precise reason for this difference, but it is possible that the target selection may be a function of the specific tissues and cell types as well as species, since the mouse targets were identified in primary cerebellar cells, and the human targets were identified in the SH-SY5Y human neuroblastoma cell line. The gene discussed is ITPR1; the disease is neuroblastoma.