For example, we have previously shown that, in a model of pulmonary fibrosis induced by bleomycin, the blockade of CXCR2, the chemokine receptor involved in neutrophil chemotaxis, led to reduced neutrophil number in BALF and protection from lung fibrosis, but there was still neutrophil accumulation in lungs at a later time point [25]. Here, CXCR2 is linked to pulmonary fibrosis.