There was no significant difference in tumor weights between the A375-G6PD∆-G6PD-G487A and A375-G6PD∆-G6PD-WT cell groups (P > 0.05), but both exhibited tumors that were larger than those observed in the G6PD deficiency group (P < 0.05, Figure 2C). The gene discussed is G6PD; the disease is hyperinsulinemic hypoglycemia, familial, 4.