These cell lines were selected they are well characterised and accepted to represent neuronal function (SK-N-AS) and breast cancer (MCF-7) because PARK7, also termed DJ-1, is associated with both breast cancer and early onset Parkinson’s disease [55,56], further they provide preliminary functional data on the ability of the PARK7 SVA to affect expression in different environments. The gene discussed is PARK7; the disease is breast carcinoma.