According to the miR Database (http://mirdb.org), MIR4718 has 156 known targets and two, microcephalin 1 (MCPH1, NM_024596) and strawberry notch homolog 1 (SBNO1, NM_018183) have known connections to human microcephaly 22–24. Here, SBNO1 is linked to microcephaly.