Moreover, as it is known that both IL-8 and TGF-β are among the cytokines secreted at high levels and specifically by the M2 monocytic phenotype [116], this finding suggests that ω-3 PUFAs may exert direct influence on the polarization of M1/M2 monocytic cells in the context of tumor microenvironment. Here, TGFB1 is linked to neoplasm.