To further investigate whether PRAME gene expression is correlated with the clinical characteristics of leukemia, Paydas [4] examined 74 patients, including 68 patients with de novo acute leukemia, 3 with chronic myeloid leukemia-blastic phase, and 3 with myelodysplastic/myeloproliferative syndrome-blastic transformation. Here, PRAME is linked to chronic myelogenous leukemia, BCR-ABL1 positive.