When the accuracies of the markers in discriminating between TB disease and infection was assessed only in HIV-uninfected children (17 QFT-IT positive children without disease and 12 QFT-IT positive children with disease), the unstimulated, antigen stimulated or antigen-specific levels of 5 markers (IFN-α2, IL-1Ra, VEGF, IP-10 and IFN-γ) showed significant differences or trends between the two groups (Table S4). This evidence concerns the gene IFNG and infection.