PLAC8 and infection: In our previous study Plac8 knockout mice treated with MLA were effectively unable to clear a C. muridarum genital tract infection over 8 weeks, with 11 of 12 mice continuing to shed C. muridarum with an average intensity of 1300 IFU/swab; all wild type C57BL/6 mice treated with MLA, 11 of 11, cleared the infection by day 40.