Neither HF IU nor fetal genotype altered expression of 3- hydroxyl-3-methylglutaryl- CoA synthase 2 (mitochondrial) (HMGS), 3- hydroxyl-3-methylglutaryl- CoA reductase (HMGR), sterol-C5-desaturase (SCD5), Cytochrome P450, family 3, subfamily A (CYP3A) and fatty acid synthase (FAS) (Table 3). This evidence concerns the gene CYP3A4 and hydrops fetalis.