Although expression levels of ZEB1 and TGFBR2 tended to be lower in pancreatic cancer cell lines and a breast cancer cell line relative to a normal pancreas (Fig. 4A), transcript and protein levels of these candidate genes were markedly reduced in mesenchymal-like pancreatic or breast cancer cells 96 hours after transfection with dsRNAs mimicking miR-655 (Fig. 4B). This evidence concerns the gene ZEB1 and pancreatic neoplasm.