Increased levels of CXCL9/MIG, CXCL10/IP-10, CXCL11/I-TAC [24], and RANTES/CCL5 [26] synthesized by keratinocytes in psoriasis lesions as well as the BRAK/CXCL14 that are upregulated in nonlesional skin of psoriasis patients [24], may also activate and initiate the migration of mononuclear leukocytes/T cells/monocytes to the psoriatic lesions. The gene discussed is CXCL11; the disease is psoriasis.