Vitamin D analogues successfully decreased the doses of conventional immunosuppressive drugs in experimental autoimmune encephalomyelitis (EAE) model [4]; furthermore, in EAE, the addition of the vitamin D analogue TX527, with reduced calcemic activity, empowered the protective effect of IFN-β and CsA regimens, suggesting that this compound could be considered for clinical intervention in MS [102]; it is of interest that an association between CXCL10 and subjects affected with MS has been previously shown [119]. Here, CXCL10 is linked to myeloid sarcoma.