These results translated into an association of leptin concentrations with high diastolic and mean blood pressure in RA but not non-RA subjects and a relationship of leptin concentrations with a high total cholesterol-HDL cholesterol ratio, triglyceride concentrations and the triglycerides-HDL cholesterol ratios in non-RA but not non-RA participants. The gene discussed is LEP; the disease is rheumatoid arthritis.