The geometric mean (SD) circulating leptin and adiponectin concentrations were 28 330.88 (2.75), 12 114.63 (2.35) pg/mL, 11.25 (1.83), and 7.28 (2.05) ng/mL in non-RA and RA participants, respectively (P < 0.0001 for both). Here, ADIPOQ is linked to rheumatoid arthritis.