The TB IRIS group had lower initial frequencies of CD38+ HLADR- cells among CM CD8+ T cells than the Other IRIS group (p = 0.0071, Figure 2B) and lower initial proportions of CD38+ HLADR- among EM CD8+ T cells than the Other IRIS and No IRIS groups (p = 0.005 and p = 0.047, respectively; Figure 2C). The gene discussed is CD8A; the disease is tuberculosis.