LOXL1 and exfoliation syndrome: Multiple replication studies in non-Scandinavian populations (United States, Australia, Europe, Japan, China, and India) [9], in the Uygur [10] and in a Pakistani population [11] confirmed genetic susceptibility of LOXL1 polymorphisms to XFS/XFG and verified the LOXL1 gene as a principal genetic risk factor for this condition worldwide accounting for almost all XFS cases.