PHLDA1 and endothelial dysfunction: This is consistent with the finding that Prdx‐1 deficiency in ApoE−/− mice causes endothelial activation (increased leukocyte rolling, endothelial P‐selectin, and vWF expression) and accelerates atherosclerosis.41 Further studies should clarify whether TDAG51‐mediated endothelial dysfunction contributes to atherogenesis.