NECTIN4 and non-small cell lung carcinoma: PVRL4 is expressed in a limited set of normal tissues—namely, skin epidermis, hair follicles, placenta, trachea, and lung (Jelani et al., 2011)—yet it becomes overexpressed in a large fraction of breast (Fabre-Lafay et al., 2007), NSCLC (Takano et al., 2009), and ovarian (Derycke et al., 2010) tumors.