At 6, 8, 10 day after infection, the percent of invasion were different rapidly, the group of PBS was 33.9%, 38.33%, 45.34%, the group of pVAX1 was 20.92%, 41.8%, 43.78%, the group of pVAX1-ficolin-A was 13.05%, 28.78%, 36.15%, the group of pVAX1- MSP119 was 3.72%, 21.05%, 33.36%, while the group of pVAX1-ficolin-A with pVAX1-MSP119 was 3.16%, 15.85%, 22.23%. Here, FCN1 is linked to infection.