Using a sample of 155 European adolescents with MDD from the TORDIA (Treatment of SSRI (selective serotonin reuptake inhibitor)-Resistant Depression in Adolescents) trial, Brent et al. provided preliminary reports of two FKBP5 genotypes (rs1360780-TT and rs3800373-GG) significantly associated with suicidal events [26]. Here, FKBP5 is linked to major depressive disorder.