A 2010 case–control study by Riley et al., compared 1,021 Irish subjects with SZ or poor-outcome schizoaffective disorder with 626 Irish control subjects, and reported nominally significant association between SZ and ZNF804A rs1344706 (P = 0.0227) and two other ZNF804A SNPs (rs17508595 at P = 0.0230 and rs7597593 at P = 0.0013) [61]. This evidence concerns the gene ZNF804A and schizoaffective disorder.