GWAS in BD have identified four genes for further study that had SNPs of genome-wide statistical significance: calcium channel, voltage-dependent, L type alpha 1C subunit (CACNA1C), ankyrin 3 (ANK3), neurocan (NCAN) and odd Oz/ten-m homolog 4 (ODZ4) [49-51]. Here, ANK3 is linked to Behcet disease.