Next, we evaluated the pCR and RFS rates in 30 and 34 patients, respectively, excluding 7 and 8 patients with HER2 copy numbers ≤ 2.0 from the 37 and 42 patients, respectively, because data on patients only with a HER2-amplified tumor may be important to show outcome of the therapy given to a specified group of patients (Additional file 2 Table S2). The gene discussed is ERBB2; the disease is neoplasm.