TTF-1 positive tumors tended to be more frequent (although not significant) in interval cancers compared with screening-detected cancers (6,7% vs. 2,0%; P = 0,12), in PR negative tumors compared with PR positive tumors (4,4% vs. 1,9%; p = 0,26), in HER2 positive tumors compared to HER2 negative (4,8% vs. 2,7%; P = 0,47) and in LVI positive cancers (4,8% vs. 2,2%; p = 0,37) compared to LVI negative tumors. This evidence concerns the gene ERBB2 and cancer.