SCN2A and Global developmental delay: Indeed, Chen et al. (2010) reported a 2.8-Mb de novo cryptic deletion on chromosome 2q24.2/q24.3 detected by array-CGH (comparative genomic hybridization), involving nine genes including SCN2A and SCN3A in a patient with autistic features, developmental delay, language impairment, mental retardation, and dysmorphic features.