ST8SIA2 and schizophrenia: Although the promoter region of the ST8SIA2 gene has not been well examined in vitro, the schizophrenia-associated haplotype block of ST8SIA2 appears to localize in the putative promoter region based on database searches (TFSEARCH, http://mbs.cbrc.jp/research/db/TFSEARCHJ.html), which identified several putative consensus motifs and transcriptional factor binding sites, including those for CCAAT, MZF1, CREB, GATA, TATA, and SP1 (Arai et al., 2006).