However, CD55 expression levels on peritoneal F4/80−Ly-6G+ neutrophils in Il-1r−/− mice were intermediate between those on cells of WT and Nod2−/− mice with CLP, indicating that NOD2-mediated IL-10 suppresses CD55 expression on peritoneal F4/80−Ly-6G+ neutrophils in both an IL-1β-dependent, and an IL-1β-independent manner during sepsis (Fig. 5D). This evidence concerns the gene CD55 and Sepsis.