DCD and type 1 diabetes mellitus: However, unlike in the case of the autoimmunity induced destruction of the pancreatic β cells as in the case of the T1DM, the dermcidin induced inhibition of insulin synthesis could be neutralized through the stimulation of systemic NO synthesis (7) and, as such, the development of the condition induced by dermcidin not necessarily destroyed the synthetic ability of the hepatocytes to produce insulin.