Among the significant proteins identified based on the STRING network (Figure 1), 11 belonged to the angiogenesis pathway or interacted with it, and 8 proteins (CA9, SLC2A1 (Glut1), SLC2A4 (Glut4), SLC2A5 (Glut5), HIF1α, VEGFA, VEGFR2 and VHL) were shown to have significant associations with proteins belonging to the angiogenesis, apoptosis, or metabolic pathways in the 80 RCC studied. Here, KDR is linked to renal cell carcinoma.