Currently, the World Health Organization recommends the following criteria for diagnosis: impaired glucose metabolism, insulin resistance, blood pressure ≥140/90 mmHg, triglycerides ≥150 mg/dl and/or HDL cholesterol <35 mg/dl in men or <39 mg/dl in women, central obesity (waist to hip ratio in males >0.90 and >0.85 in women and/or BMI >30 kg/ m2), and microalbuminuria (urinary albumin excretion rate ≥20 μg/min or albumin:creatinine ratio ≥30 mg/g). The gene discussed is ALB; the disease is Abdominal obesity.