It was found that CD4+T cell infiltration in colon inflammation, expansion in peripheral blood, and CD4 protein expression up-regulation were showed in animals suffering from intestinal inflammation and that the resistance of RTP on the expansion of CD4+T cell was presented significantly in both SD rats and BALB/c mice (Figures 3, 4 and 5) (Table 3). The gene discussed is CD4; the disease is gastroenteritis.