The apoE content of VLDL with apoC‐III, expressed as the apoE:apoB molar ratio in this fraction, also showed a strong negative association with CHD (relative risk for top versus bottom quintile 0.50, 95% CI 0.35 to 0.72; P for trend <0.001) that persisted after additional multivariable adjustment in models 2 and 3 (Table 2 and Figure 2). This evidence concerns the gene APOC3 and coronary artery disorder.