Adjustment for plasma LDL cholesterol in the background of multivariable model 3 only slightly attenuated the negative association between apoE content of LDL that has apoC‐III and CHD (relative risk 0.62, 95% CI 0.41 to 0.93) and between apoE content of VLDL that has apoC‐III and CHD (relative risk 0.61, 95% CI 0.40 to 0.93). Here, APOC3 is linked to coronary artery disorder.